Assembly and Release of HIV-1 and Other Retroviruses

A postdoctoral position is currently available in a research program focused on a variety of key aspects of HIV-1 assembly and release. Of particular interest are the interplay between viral and host factors in the targeting of assembly to the plasma membrane, the role of lipid rafts in membrane association and virus assembly, and the mechanism by which the viral envelope glycoproteins are incorporated into virions. Recent studies have been aimed at defining the cellular pathways and host factors involved in the budding of retrovirus particles from the plasma membrane and identifying inhibitors of virus budding and entry. Studies are also underway to define the target and mechanism of action of a novel HIV-1 maturation inhibitor. Further details and a list of relevant publications can be found at http://home.ncifcrf.gov/hivdrp/Freed.html.

Interested candidates must possess a Ph.D. and/or an M.D. and have a strong background in molecular biology, biochemistry, and/or virology. The salary range is commensurate with experience. To apply, submit a cover letter, curriculum vitae, bibliography, and names of three references to:

Dr. Eric O. Freed
HIV Drug Resistance Program, National Cancer Institute
Frederick National Laboratory for Cancer Research
P.O. Box B Building 535, Room 110
Frederick, MD 21702-1201
E-mail: efreedmail.nih.gov
Website: http://home.ncifcrf.gov/hivdrp/Freed.html

Application deadline: June 30, 2013

This position is subject to a background investigation.
The NIH is dedicated to building a diverse community in its training and employment programs.