A postdoctoral position is available at the Laboratory of Malaria and Vector Research. We have identified novel ion channels and transporters in malaria parasites. These transport proteins are required for intracellular parasite development and are being pursued as model microbial channels and antimalarial drug targets. One project uses CRISPR/Cas9 gene editing to examine mechanisms of nutrient uptake by the parasite. Another project, antimalarial drug development targeting an essential parasite ion channel, is being pursued with academic and pharmaceutical partners through NIH and external grants. Our lab is highly multi-disciplinary, combining cell and molecular biology, biochemistry, structural biology, chemical biology including high-throughput screening, and other technologies.
The candidate may use molecular biology (CRISPR/Cas9 editing, heterologous expression), cell biology (biochemical methods such as transport assays developed in our lab or electrophysiology), drug discovery methods, structural biology methods (cryoEM, x-ray crystallography), and/or a range of other methods. Our laboratory consists of a motivated, close-knit group of scientists from diverse backgrounds and research training. Additional information can be found at https://www.niaid.nih.gov/research/sanjay-desai-md-phd
- A PhD in cell biology, molecular biology, or related
- Ability to conduct independent research and work cooperatively with other scientists.
- Excellent communication skills
Interested applicants should email Sanjay Desai, M.D., Ph.D. at sdesainih.gov. Please send a cover letter, curriculum vitae, and the names, phone numbers and e-mail addresses of three professional references. Applications will be accepted until the position is filled.
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