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Investigating the structure and function of centrosomal protein complexes using X-ray crystallography, EM, or classical cell biological approaches including super-resolution imagingPosted by: National Institutes of Health (NIH)
Posted date: 2017-Mar-17
Kang, Y.-H., et al. 2006. Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol. Cell 24:409-422.
Soung NK, et al. 2009. Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. Dev. Cell 16: 539-550.
Park JE, et al. 2009. Direct quantification of polo-like kinase 1 activity in cells and tissues using a highly sensitive and specific ELISA assay. PNAS USA. 106:1725-1730.
Yun SM, et al. 2009. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat. Str. & Mol. Biol. 16:876-882.
Park, J. -E., et al. 2011. Feed-forward mechanism of converting biochemical cooperativity to mitotic processes at the kinetochore plate. PNAS USA. 108:8200-5.
Johmura Y, et al. 2011. Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1. PNAS USA. 108:11446-11451.
Liu F, et al. 2011. Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel. Nat. Chem. Biol. 7:595-601.
Lee KH, et al. 2012. Identification of a novel Wnt5a-CK1-Dvl2-Plk1-mediated primary cilia disassembly pathway. EMBO J. 31:3104-17.
Park, S. -Y., et al. 2014. Molecular basis for unidirectional scaffold switching of Plk4 in centriole biogenesis. Nat. Str. Mol. Biol. 21:696
Lee, K. S., T. R. Burke, J. -E. Park, J. K. Bang, E. Lee. 2015. Recent advances and new strategies in targeting Plk1 for anticancer therapy. Trends in Pharmacological Sciences. 36:858-877 (review).
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