A post-doctoral fellowship is available beginning January 2018 in the Laboratory of Biochemistry and Genetics to model human diseases in C. elegans. We use CRISPR/Cas9 genome editing to generate mutations in C. elegans that are orthologous to human disease mutations. We then use genetic, molecular, and cell biological approaches to characterize the mutant phenotypes as well as characterize the wild-type expression pattern of the disease gene. Suppressor screens will be carried out to identify other factors that interact with each disease gene in its given biological process. Our laboratory is located within the National institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health in Bethesda, MD, USA. For more details, please see our web site at:
The ideal candidate will be highly motivated to develop their own research program and possess a PhD or MD degree with a strong background in genetics, biochemistry, and/or molecular and cellular biology. Good oral and written communication skills are required. Applicants must have less than 5 years of post-doctoral experience.
Qualified individuals should send a cover letter describing research experience and interests and long-term career goals, curriculum vitae, bibliography, and contact information for three references (including the current supervisor) to:
Dr. Andy Golden at andygnih.gov.
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