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Postdoc Fellow: NeuropharmacologyPosted by: National Institutes of Health (NIH)
Posted date: 2018-Aug-07
1. Role of microglia in inflammation–related neurodegeneration
Using both primary midbrain neuron/glia co-cultures and in vivo study, we have developed an inflammation-induced rodent Parkinson’s disease model by employing different inflammagens such as endotoxin, LPS, β-amyloid peptides, and the pesticide, rotenone. We are interested in understanding the molecular mechanisms underlying microglia-mediated neurotoxicity through the investigation of pro-inflammatory factors released from microglia and how these factors exert their toxic effects on neurons. In addition, we are also interested in studying the signaling pathways underlying the regulation of the gene expression of these pro-inflammatory factors in microglia and other related immune cells
2. Development of potential therapeutic interventions in inflammation-related diseases
Applicants must have received a Ph.D. or equivalent degree, and have extensive experience in Neuropharmacology, Neurochemistry or Molecular Biology.To Apply:
Please send a cover letter, curriculum vitae, and statement of research interests. In addition, please arrange to have three letters of recommendation sent by three scientists.
Dr. J. S. Hong
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