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Epigenetics and Gene ExpressionPosted by: National Institutes of Health (NIH)
Posted date: 2018-Oct-06
The Eukaryotic Transcriptional Regulation Group (Wade Laboratory) at the National Institute of Environmental Health Science is seeking highly motivated individuals interested in the fundamental principles of chromatin structure and gene regulation. Our research program studies regulation of gene expression through chromatin mediated mechanisms, focusing on histone modification and chromatin remodeling (see for example Takaku et al., 2018, Nature Communications 9: 1059. doi: 10.1038/s4167-018-03478-4.; Li et al., 2018 Cell Reports 22(3):624-637; Qin et al., 2018 Genome Biology 19: 7. doi: 10.1186/s13059-018-1389-1). Current work addresses gene regulatory paradigms focusing on the Mi-2/NuRD complex, transcription factor action within chromatin, and animal models of disease. Successful candidates will lead projects that incorporate state of the art technologies, including epigenomics and biochemistry in cellular and animal models.Qualifications:
The ideal candidate will have an MD or PhD in life sciences with a strong background in cell and molecular biology, genetics, epigenetics, transcriptional regulation, or biochemistry with less than two years of postdoctoral experience Recent graduates are encouraged to apply. Experience with mouse models or with chromatin biology is helpful. Desired qualities include the ability to work in a team, a passion for science, and excellent communication skills.
The NIEHS offers many advantages for postdoctoral training. The Epigenetics and Stem Cell Biology Laboratory at NIEHS (https://www.niehs.nih.gov/research/atniehs/labs/escbl/index.cfm) is a highly collaborative, fast-paced, intellectually challenging academic environment. NIEHS features numerous state of the art core facilities (https://www.niehs.nih.gov/research/atniehs/facilities/index.cfm) and specialized equipment, with opportunities for training. The Office of Fellows Career Development (https://www.niehs.nih.gov/careers/research/fellows/index.cfm) offers support for career development and exploration of alternative career paths.To Apply:
This is a 100% time research position. All interested applicants should submit a letter of interest, CV, and contact information for at least three references. For questions regarding the position, please contact:
Dr. Paul Wade
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