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Postdoctoral Fellow: Translational Inflammatory Disease ResearchPosted by: National Institutes of Health (NIH)
Posted date: 2019-Jan-30
Due to a unique funding mechanism provided for a NIA-NIEHS Joint Two-Year Fellowship Award, the Section on DNA Helicases, Laboratory of Molecular Gerontology, NIA and Clinical Research Branch/Environmental Autoimmunity Group, NIEHS is recruiting a postdoctoral fellow to work on a project entitled: “Functional Significance of Mutations in Helicase Genes in Patients with Juvenile Dermatomyositis and anti-MDA5 Autoantibodies”. The project will entail molecular-genetic characterization of mutations causing autoinflammatory diseases in children and further delineation of inflammatory pathways that can potentially be targeted therapeutically. The Postdoctoral Fellow will, through these studies, attempt to determine the etiology and mechanisms of autoimmune disease, relevant to environmental stimuli and increases in aging populations. Helicase mechanisms will be explored to acquire a better understanding of their roles in aging and inflammation, as they pertain to decline in immune function. The Fellow will also collaborate with researchers at the NIH Clinical Research Center (Lisa Rider, M.D.) and NIAID (Raphaela Goldbach-Mansky, M.D., MHS).
The successful applicant will be expected to perform mechanistic studies, analyze the resulting data, prepare and submit manuscripts, and present at scientific conferences. The applicant is required to have a strong background in molecular biology, with expertise in mammalian tissue culture and immunology desirable. Excellent writing skills, a strong publication record, and the ability to work independently are required. Computer skills and the ability to integrate information from multiple sources are a plus.Qualifications:
Division of Intramural Research (DIR)
Application Deadline Date: February 15, 2019To Apply:
Interested applicants should send a cover letter explaining their research background, accomplishments, and goals; a curriculum vitae; and the names and contact details of three references jointly to Frederick Miller, M.D., Ph.D. (NIEHS; millerfmail.nih.gov) and Robert Brosh, Ph.D. (NIA; broshrmail.nih.gov).
HHS, NIH, and NIA, and NIEHS are equal opportunity employers. The NIH is dedicated to building a diverse community in its training and employment programs.