We have changed our domainWe have changed servers and operate Career|edu under a different domain. Our services will remain unchanged and we will continue to post the best career openings for the academic world at our new domain.
Go back to the Job List
PhD position, Bio-electrochemistry - 2019BAPFWETEF185Posted by: University of Antwerp
Posted date: 2019-Jun-25
The AXES research group at the University of Antwerp (http://www.axes.be/) has an open position for a PhD to strengthen our developments in the field of bio-electrochemistry.
The on-site and higly selective detection of low molecular weight target molecules remains a challenging area of research. In this project, we wish to better understand and eventually improve analytical detection systems that use short DNA sequences for selective recognition of molecules of interest – called aptamers – followed by the generation of electrical signals upon binding.To achieve this we will first study the fundamental influence of structure and flexibility of aptamers on binding and current generation. This will further be mapped using computer modelling, NMR spectroscopy and ITC measurements. After obtaining structural knowledge, we aim to chemically stabilize the high affinity aptamers by introduction of chemically modified building blocks in the aptamer nucleic acid sequence. The additional functional groups thus introduced in the aptamer should allow to enhance the stability of the folded ligand binding state of the aptamer. In this way, we hope to contribute to the development of more robust aptasensors. This should ultimately and on the long term lead to improved, robust, simple and mobile devices allowing to be handled on-site in different fields of application (e.g. law enforcement agencies, medical care environment, food industry).
PhD position in Science in the field of bio-electrochemistry
Profile and requirements
How to apply?
The University of Antwerp is a family friendly organization, with a focus on equal opportunities and diversity. Our HR-policy for researchers was awarded by the European Commission with the quality label HR Excellence in research.
We support the Science4Refugees initiative and encourage asylum-seeking, refugee scientists and researchers to apply for a job at the University of Antwerp.