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Human Molecular Genetics, Genetic Susceptibility to Lung Cancer and MelanomaPosted by: National Institutes of Health (NIH)
Posted date: 2019-Jul-01
A new research group in the Laboratory of Translational Genomics (LTG) under the Division of Cancer Epidemiology and Genetics (DCEG) of the National Cancer Institute is seeking candidates for postdoctoral positions in the laboratory of Jiyeon Choi Ph.D.
The new research program will study genetic susceptibility to common cancers including melanoma and lung cancer, focusing on mechanistic understanding of population-scale genomic data such as those from genome-wide association studies (GWAS). The goal is to identify genes and molecular pathways through which heritable genetic variants confer increased cancer risk and eventually improve cancer prevention and therapy. The group will also explore deconvoluting genetic and non-genetic factors contributing to lung cancer risk by participating in Sherlock-lung study (a large-scale collaborative genomic/epidemiologic study of lung cancer in never-smokers; https://dceg.cancer.gov/research/cancer-types/lung/sherlock-lung-study).
The position offers an opportunity to explore molecular mechanisms of lung cancer and melanoma susceptibility by identifying genes and pathways contributing to the risk from GWAS data. A wide range of functional genomics approaches will be adopted including eQTL, MPRA, RNAseq, Hi-C, and CRISPR-screening. Conventional approaches of molecular genetics and cancer biology will also be used to characterize gene function in tumor-promoting potential. The focus of this position will be leading/co-leading international collaborative projects, while working closely with bioinformaticians and statisticians. Opportunities for learning computational skills and statistical genetics as well as mentoring postbacs or summer students will be available based on interest.
LTG provides a unique collaborative and collegial environment with multiple groups studying different cancers while collaboratively developing/adopting cutting-edge techniques and methodologies. DCEG and NIH provide multiple channels of supporting career development and wellbeing of postdoctoral fellows.
For more information about this position, please contact Jiyeon Choi, Ph.D.; Email: jiyeon.choi2nih.gov.Qualifications:
Candidates must have completed or will soon complete a Ph.D. with an emphasis in Molecular Biology, Cell Biology, Cancer Biology, Human or Mouse Genetics, Population Genetics, or related areas within the past 5 years. A demonstrated ability to work in a multidisciplinary and diverse team and clear communication skills will be favored. Experience with lung cell culture will be a plus. Salary will be determined based on NCI stipend schedule for postdoctoral fellows.To Apply:
Please send a cover letter, curriculum vitae including bibliography, and the names/contact information of three references to jiyeon.choi2nih.gov. This position is subject to a background investigation.
The NIH is dedicated to building a diverse community in its training and employment programs.