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Structural BiophysicsPosted by: National Institutes of Health (NIH)
Posted date: 2019-Aug-24
Postdoctoral positions are currently open in Dr. Ping Zhang’s research group (https://ccr.cancer.gov/Structural-Biophysics-Laboratory/ping-zhang) at the Structural Biophysics Laboratory (SBL), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH). Dr. Zhang’s laboratory is located at NIH’s vibrant campus at Frederick, Maryland, about one-hour drive from Washington DC. (https://ncifrederick.cancer.gov/About/).
Dr. Zhang’s group studies the structural and mechanistic basis of kinases that are closely related to human cancers and many other diseases. Our main focus is on oncogenic kinases (including ALK, BRAF, Leucine Rich Repeat Kinase and PKA). We have also developed new collaborations within the CCR involving projects with propensity for translational application to the clinic, including the study of nucleosome complex and Microprocessor complex. We apply a combination of biochemical and structural (single-particle cryo-electron microscopy and X-ray crystallography) approaches to reveal the molecular mechanisms of such multi-component biological complexes and help to provide new strategies for therapeutic targeting.
The research of the group is supported by the collaborative and interdisciplinary NIH intramural program, which includes more than 1100 labs and provides state-of-the-art equipment in structural biology, biochemistry, and biophysics. These core facilities are supported by Ph.D-level staff and offer hands-on training. In addition, NIH is committed to the continuing education and career development of its research staff through numerous courses and workshops offered by NIH Office of Intramural Training & Education (OITE) and Foundation for Advanced Education in the Sciences (FAES). There are also opportunities for intramural career transition funding (K grants).Qualifications:
The candidate must have received a Ph.D. or M.D. degree within the past five years (or expecting one before Fall) in molecular biology, structural biology, biochemistry, or a related discipline. The candidate should have good oral and written skills in English. The candidate ought to be skilled in at least one of the following areas:
The candidate must be highly motivated to participate in rigorous and innovative research programs, and possess excellent work ethic and team spirit: be able to work independently and efficiently and collaborate closely with members of the group and other labs on joint projects.To Apply:
Please email a cover letter indicating preferred starting date, a brief description (1-2 pages) of past research, CV, and contact information for at least three references to ping.zhangnih.gov. Please state your area of interest in the application. Projects will be considered based on the applicant’s experience, interest, and creativity.
The NIH is dedicated to building a diverse community in its training and employment programs. This position is subject to a background investigation.