Environmental Regulation of the Estrogen Response in Single Cells

A postdoc position is available in the laboratory of Dr. Rodriguez in the Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH in Research Triangle Park, NC. We are interested in eukaryotic gene regulation and how environmental stimuli modulate the single cell estrogen response. Our long-term goal is to understand how heterogeneity in the hormone response contributes to tissue function and disease. The lab uses a variety of imaging and sequencing approaches including live and fixed cell single-molecule microscopy. Projects in the lab include determining how local environment and chemical exposure affect estrogenic transcriptional activity in breast cancer cell lines, organoids and mice.

PhD in molecular/cell biology, genomics, biochemistry or relevant field. We are looking for postdoc candidates with experience in epigenetics, transcription, RNA, or single cell biology. Experience working with organoids or mice is a plus. No prior experience in microscopy is necessary.

Interested candidates should send a short statement of how your interests and research accomplishments fit with interests in the lab, CV and contact information for 3 references to Joseph.Rodrigueznih.gov.

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