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Organic and Medicinal ChemistryPosted by: National Institutes of Health (NIH)
Posted date: 2019-Sep-20
A postdoctoral position is available for an organic chemist to work on multi-step synthesis of mostly nitrogenous small molecules on a multigram scale in the Drug Design and Synthesis Section, National Institute on Drug Abuse (NIDA), 9800 Medical Center Drive, Rockville, Maryland. Our major research direction is the elucidation of the structure and function of neurotransmitter systems in the mammalian central nervous system (CNS) in normal, drug-altered, and pathological states and the molecular mechanism of action of CNS active drugs.
DDSS has been involved with the rational design and chemical synthesis of novel agonists, antagonists, imaging agents, and affinity ligands as well as haptens for anti-heroin and anti-fentanyl vaccines and highly biased G-protein mu-opioid ligands. For more information, please visit: https://irp.drugabuse.gov/Rice.php.Responsibilities:
Incumbent will collaborate with colleagues in various pharmacological and other diverse scientific disciplines and must possess good interpersonal and organizational skills and excellent communication skills with fluency in both spoken and written English. The incumbent will be responsible for maintaining laboratory notebooks with complete records of all scientific experiments and raw data and be able to prepare technical reports, manuscripts, patent applications as needed, and present work orally at seminars internally and at national and local scientific meetings.Qualifications:
Candidates should be very close to obtaining a Ph.D. or have a Ph.D. with less than two years of postdoctoral experience, demonstrated experience in synthetic organic/medicinal chemistry with emphasis on heterocyclic chemistry, and an ability to work independently. The incumbent must be able to synthesize, purify, crystallize, optically resolve, identify, characterize and analyze new compounds (HRMS, 1HNMR , 13CNMR, HPLC, optical rotation) and search the chemical literature under the supervision of senior staff.To Apply:
Qualified individuals should send a cover letter with a brief description of goals and interest, curriculum vitae, bibliography, and contact information for three references (including the current supervisor) to: Mariena Mattson, Lab Manager, Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, DHHS/NIH/NIDA, 9800 Medical Center Drive, Rm 239A, Rockville, MD 20892-3373; E-mail: mattsonmmail.nih.gov.
The NIH is dedicated to building a diverse community in its training and employment programs. This position is subject to a background investigation.