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ImmunometabolismPosted by: National Institutes of Health (NIH)
Posted date: 2019-Sep-26
A postdoctoral position is available in Dr. Powell-Wiley’s laboratory in the Cardiovascular Branch of NIH, National Heart, Lung, and Blood Institute (Bethesda, MD). Dr. Powell-Wiley is an NIH Earl Stadtman Investigator and Chief of the Social Determinants of Obesity and Cardiovascular Risk Laboratory at NHLBI. The lab is supported by state-of-the-art core facilities, like the flow cytometry, RNA sequencing, proteomics, bioinformatics, and advanced microscopy cores. With an interdisciplinary research environment and strong intramural support, this position provides a unique opportunity for recent PhD awardees to deepen and broaden their research profile for advancing to an independent academic career.
The Powell-Wiley group studies the impact of chronic stress from environmental factors on the development of obesity and cardiovascular disease risk with the goal of identifying underlying mechanisms by which social and physical environmental stressors alter immune cell function and metabolism. The main goal of this translational research laboratory is to examine the regulation of immunometabolic pathways related to obesity and cardiovascular risk in natural killer (NK) and monocyte cell populations by neurotransmitters and/or specific chronic stressors. Furthermore, the laboratory is working to examine the effects of health behavior interventions on these immunometabolic pathways in humans in an effort to identify cellular and signaling pathways most amenable to changes in cardiovascular disease risk by health behavior change.
More information on the Powell-Wiley group is available at: https://irp.nih.gov/pi/tiffany-powell-wiley.Responsibilities:
The post-doctoral fellow’s position in the laboratory would be to perform immunometabolic phenotyping of the primary cells extracted from clinical study participants and then identify and characterize molecular pathways governing these effects. Subsequent intervention studies would then be implemented to evaluate whether obesity or psychosocial stressor amelioration will rescue these aberrant regulatory and immunometabolic pathways.Qualifications:
The ideal candidate must have a PhD or MD/PhD with a strong background in immunometabolism, cell biology, molecular biology and/or immunology. Experience in the field of neuroimmunology, psychoneuroimmunology, and/or neurotransmitter research is desirable but not necessary. The candidate must be within 5 years of receiving their doctoral degree and is expected to display a reasonable level of independence, be innovative and be a team player. This position is fully supported by NIH intramural funds and successful candidates will be offered competitive stipend/health insurance commensurate with experience and accomplishments.To Apply:
Applicants should send a 1-2 page descriptive letter of interest, curriculum vitae and 3 letters of reference to be sent (via email only) to: tiffany.powell-wileynih.gov. Applications will be continuously reviewed until the position is filled.
Applications from women, minorities and persons with disabilities are strongly encouraged. HHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.