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Postdoctoral Research Associate - Childhood LeukaemiaPosted by: Postdoc positions by NIH
Posted date: 2019-Sep-27
An exciting opportunity has arisen to join the Childhood Leukaemia Research Group led by Professor Anindita Roy at the University of Oxford. The group’s research explores how childhood leukaemia develops before birth, with a focus on treatment resistant infant leukaemia. This post is funded by a generous grant from the Wellcome Trust.
We are seeking a motivated and enthusiastic Postdoctoral Researcher to lead a project designed to understand how developmental stage specific characteristics of human B lymphopoiesis determines the biology of leukaemia. The project will involve state-of-the-art techniques such as single-cell multi-omics including scRNAseq, in vitro assays, proteomics and in situ imaging of normal and leukaemic samples; as well as modelling of MLL-AF4 leukaemia using CRISPR-Cas9 followed by xenograft assays. The postholder will be well supported by an experienced multi-disciplinary research team which includes other postdoctoral research assistants and DPhil students in the lab, computational biologists, clinicians, as well as members of collaborating labs.
The postholder will be based at the MRC Weatherall Institute of Molecular Medicine (MRC WIMM), John Radcliffe Campus of University of Oxford in the laboratory of Professor Anindita Roy and Professor Irene Roberts. The MRC WIMM is a world-class research institute with excellent core facilities, fostering research in molecular and cell biology with direct application to human diseases with a particular focus on haematology, oncology, immunology, stem cells and computational biology.
This is a full-time new fixed-term appointment for 3 years in the first instance with possibility of extension for a further 2 years.Qualifications:
The successful candidate will be an experienced researcher holding or close to completing a PhD in molecular/cellular biology, haematology or other relevant subject. Experience in one or more of the core techniques for the project (molecular biology, multicolour flow cytometry, imaging, cell culture, xenograft models, animal handling) is essential, and a demonstrable interest in developmental haematopoiesis and/or leukaemia biology would be advantageous. The successful candidate will be responsible for managing their own research, contributing to new ideas for research projects, developing ideas for generating income, preparing scientific reports, writing up results for publication in international peer-reviewed journals, assisting other members of the group or people working on collaborative projects, and advising on scientific protocols.To Apply:
You will be required to upload a CV and supporting statement as part of your online application at https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=143151.
Please contact Professor Anindita Roy (anindita.roypaediatrics.ox.ac.uk) for further information about the post (Vacancy ID: 143151). Only applications received before 12.00 (noon) on Monday 28 October 2019 will be considered. Interviews will be held within 2 weeks of the closing date.