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Bioinformatics/OncologyPosted by: Postdoc positions by NIH
Posted date: 2019-Nov-27
The Bioinformatics Team within the Center for Data-Driven Discovery in Biomedicine (D3b - d3b.center) at the Children’s Hospital of Philadelphia (CHOP) is seeking a talented postdoctoral fellow to carry out a mentored, bioinformatics (computational) research project within the field of oncology, focused on discovery of novel oncogenic mechanisms of pediatric brain tumors. The postdoc experience will serve to extend, refine, and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities.Responsibilities:
It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. Postdocs will be expected to participate in project planning, recording, and interpretation/evaluation of data, and communication of results. Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to supervise junior team members, develop new bioinformatics methods for research, and assist with the development of other research projects in the center. Responsibilities include:
Pre-Analysis (20%) - Contribute to the development of application portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provide efficient data management support:
Coding (20%) - Code and generally support code and applications on behalf of collaborative project and/or team:
Data Analysis (20%) - Analyze data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data primarily under the direction of the collaborative project team:
Collaboration (20%) - Establish role within collaborative project team as primary bioinformatics resource:
Academic Output (20%) - Develop presentations, grant sections, and manuscript sections with subsequent review by peers and mentors:
This candidate will have a terminal degree PhD, MD, DVM, etc. and will assume responsibility for a specific, on-going research project under the direction/guidance of Dr. Jo Lynne Rokita (within the D3b center led by Drs. Adam Resnick and Jay Storm). The postdoctoral fellow will generate hypotheses and utilize and integrate WGS, RNA-Seq, and potentially extend analyses to include miRNA-Seq, methylation arrays, single-cell RNA-Seq, proteomics, and/or drug screen data. Current research projects in the group include characterization of pediatric brain tumors with alternative lengthening of telomeres (ALT), gene fusion annotation and prioritization, and genomic characterization of brain tumor models.Qualifications:
Interested candidates should contact Jo Lynne Rokita, PhD, Supervisory Bioinformatics Scientist, at rokitaemail.chop.edu.