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Immunosenescence - SignalingPosted by: Postdoc positions by NIH
Posted date: 2019-Dec-20
A postdoctoral position is open in the “Integrative mapping of lymphocyte signaling and function lab” headed by Renaud Lesourne and Loïc Dupré at the Center for Pathophysiology of Toulouse Purpan (https://www.cptp.inserm.fr/en/). The research program aims at identifying molecular networks governing T cell senescence and exhaustion during ageing. This will be explored by applying systemic approaches, including phosphoproteomics, high-content cell imaging and metabolomics to genetically engineered human T cells and murine models. Data sets will be integrated via a collaborative computational biology support and training opportunities will be provided.
The project will benefit from a lab environment dedicated to the detailed mechanistic understanding of the biology of T lymphocytes in the context of health and disease. Our lab has assembled an original combination of technological expertise, mainly quantitative microscopy approaches and proteomics to unravel novel molecular mechanisms that tune lymphocyte signaling and to investigate how such mechanisms control functional responses in vivo in murine models.
The Center of Pathophysiology of Toulouse-Purpan (CPTP) provides a stimulating environment to perform state-of-the-art research in immunology and infectious diseases, with integrated on-site technological facilities. Research teams at the CPTP host international trainees of various nationalities, ranging from undergraduate students to postdocs. External seminars and lab meetings are held in English. The CPTP is located in Toulouse, a dynamic city in the Southwest of France, 1-hr away from Paris by plane.
The position is fully funded (2 years with an extension option) and is expected to start between January and June 2020. Depending on experience, net salary may range from 2036 € to 2337 € / mo, including health benefits. Applicants should have (or be within a few months of obtaining) a PhD in immunology, biochemistry, or a similar field, with no more than 5 years of post-doctoral experience. We are seeking a highly motivated candidate associating a solid publication record with experience in mass spectrometry, biochemistry and molecular biology.To Apply:
Please send your application with CV, a statement of interest, a brief outline of previous research and contact info for 2 references to Renaud Lesourne: renaud.lesourneinserm.fr and loic.dupreinserm.fr