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Neural Crest Development and DiseasePosted by: National Institutes of Health (NIH)
Posted date: 2020-Feb-14
A postdoctoral fellow position in neural crest stem cell research is available in the laboratory of Dr. Laura Kerosuo at the Neural Crest Development and Disease Unit at the intramural program of the National Institute of Dental and Craniofacial Research at the National Institutes of Health. The laboratory is located in the dynamic and collegial Bethesda, MD, campus in the greater Washington D.C area. The Kerosuo lab is supported by extraordinary resources provided by advanced imaging, high-throughput sequencing, proteomics, bioinformatics and mouse transgenic core facilities at the institute. With an interdisciplinary research environment and strong intramural support, this position provides a unique opportunity for a recent PhD awardee to deepen and broaden their research profile for advancing to an independent academic career while the NIH training resources also provide vast support for pursuing a career outside academia.
The Kerosuo Lab studies mechanisms that guide early stages of neural crest development, how their stemness properties are formed and maintained, and how fate choices ultimately are made. We recently identified the existence and analyzed the transcriptional profile of a transient neural crest stem cell niche residing within the dorsal midline in the closing neural tube, which suggest a more pluripotency-like nature of the neural crest cells than previously thought (Nature Communications 2020). This finding prompted a myriad of questions on the function and formation of the niche. We use sophisticated cutting-edge imaging and single cell level technology to answer our questions by using the chick embryo as our in vivo model, as well human ESC derived neural crest cultures to parallel our results with human development. In addition to molecular developmental biology research on normal development, the lab also has strong interests and a functional set up by using iPSC and animal models to address mechanisms that cause neural crest derived birth defects and cancer. We are a diverse group of people motivated to do high quality science. More information about the Kerosuo lab is available at https://www.nidcr.nih.gov/research/research-conducted-at-nidcr/neural-crest-development-disease-unit.
These positions are fully supported by NIH intramural funds and successful candidates will be offered competitive stipend/health insurance commensurate with experience and accomplishments.Qualifications:
Interested candidates must be completing or should have obtained a Ph.D. or M.D. degree with background in Molecular Biology, Developmental Biology, Cell Biology, Biochemistry, or a related discipline. Experience in developmental, stem cell and cancer biology together with strong computational skills are highly desirable but not required. In general, quality of past research is more important than experience in a specific field. The candidate is expected to have the ability to conduct semi-independent research and function as part of an interdisciplinary team.To Apply:
Applicants should send curriculum vitae and 3 letters of reference (via email only) to: laura.kerosuonih.gov. Applications will be continuously reviewed until the position is filled.
The NIH is dedicated to building a diverse community in its training and employment programs. Applications from women, minorities and persons with disabilities are strongly encouraged.