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Gene Regulation in Immune Cells and Neurodegenerative DiseasesPosted by: National Institutes of Health (NIH)
Posted date: 2020-Mar-13
Postdoctoral positions are available in the laboratory of Dr. Han-Yu Shih in Neuro-Immune Regulome Unit at NEI/NINDS. Emerging evidence indicate a role of immune system in neurodegenerative diseases; however, how pro-inflammatory molecules and immune cells are involved in disease onset and pathogenesis remains largely unknown. Our lab aims to understand the role of lymphocytes and cytokines in the progression of neurodegenerative disorders such as Alzheimer’s disease and Age-related macular degeneration in animal models. Using unbiased genomic approaches including single cell RNA-seq, single cell ATAC-seq, ChIP-seq or Cut&Run, Hi-C and CRISPR-screening, we seek to identify novel regulatory pathways for therapeutic targets.
This position offers exposure to multidisciplinary and cutting-edge genomic researches and opportunities to collaborate closely with experts in immunology, neurobiology and bioinformatics. The candidates will be leading/co-leading projects, designing experiments for generating high-dimensional data while working closely with collaborators and lab mates. Opportunities for training in immunology and bioinformatics as well as mentoring postbacs or summer students will be available based on interest.Qualifications:
Interested candidates should send a cover letter, curriculum vitae, bibliography, a paragraph of research interest and contact information of three references to: Han-Yu Shih (han-yu.shihnih.gov).
This post will be available until June 13, 2020.
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